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International Journal of Chemical Research and Development

Vol. 6, Issue 1, Part A (2024)

Synthesis, characterisation and antimicrobial activity of n-substituted 2-thiohydantoin derivatives

Author(s):

Prashant A Gotmare and Dr. Sanjay V Kolhe

Abstract:

Novel 2-thiohydantoin derivatives (1a and 1b) were synthesized from aurones with solvent ethanol. The structures of synthetic compounds were characterized using Fourier-transform infrared spectroscopy (FT-IR), 1H-nuclear magnetic resonance (NMR) spectroscopy, and mass spectrometry. Synthesized compounds shows good to moderate antibacterial and antifungal activities against Bacterial culture, Escherichia coli (MTCC-452), Pseudomonas aeruginosa (MTCC-3541), Mycobacterium tuberculosis (MTCC-300), Enterococcus faecalis, Aspergillus niger, (MTCC-281), Candida. Albicans, (MTCC- 854) species.

Pages: 01-03  |  245 Views  119 Downloads


International Journal of Chemical Research and Development
How to cite this article:
Prashant A Gotmare and Dr. Sanjay V Kolhe. Synthesis, characterisation and antimicrobial activity of n-substituted 2-thiohydantoin derivatives. Int. J. Chem. Res. Dev. 2024;6(1):01-03. DOI: 10.33545/26646552.2024.v6.i1a.59