Shivakumara K N, Sridhar B T
Compounds comprising urea and thiourea are progressively more used in drug design and medicinal chemistry to facilitate key drug-target communications and fine-tune crucial drug-like properties. Urea and thiourea represent privileged structures in medicinal chemistry. Certainly, these scaffolds encompass a common structure of a array of drugs and bioactive compounds artistic with a expansive range of beneficial and pharmacological properties. Herein, we provide an overview of urea and thiourea based medicinally important compounds, ranging from standard drugs to current medicinal chemistry developments.
Pages: 20-25 | 597 Views 335 Downloads