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International Journal of Chemical Research and Development

Vol. 3, Issue 1, Part A (2021)

Review on role of urea and thiourea derivatives of some heterocyclic Scaffold in drug design and medicinal chemistry

Author(s):

Shivakumara K N, Sridhar B T

Abstract:

Compounds comprising urea and thiourea are progressively more used in drug design and medicinal chemistry to facilitate key drug-target communications and fine-tune crucial drug-like properties. Urea and thiourea represent privileged structures in medicinal chemistry. Certainly, these scaffolds encompass a common structure of a array of drugs and bioactive compounds artistic with a expansive range of beneficial and pharmacological properties. Herein, we provide an overview of urea and thiourea based medicinally important compounds, ranging from standard drugs to current medicinal chemistry developments.

Pages: 20-25  |  743 Views  379 Downloads

How to cite this article:
Shivakumara K N, Sridhar B T. Review on role of urea and thiourea derivatives of some heterocyclic Scaffold in drug design and medicinal chemistry. Int. J. Chem. Res. Dev. 2021;3(1):20-25. DOI: 10.33545/26646552.2021.v3.i1a.23